"Osteopetrosis" in the Fairbank Collection.

Mixed Sclerosing Bone Dystrophies

Many of the sclerosing bone dystrophies fall within the classification employed by Fairbank (1951). However, patients occasionally present features suggesting a possible relationship between osteopoikilosis (spotted bones), osteopathia striata (striated bones, Voorhoeve’s disease), melorheostosis (running wax bones) and osteopetrosis (dense or marble bones). Areas of dense bone arranged in diff...

Osteopetrosis a report of two Iranian patients with autosomal recessive inheritance pattern

In the rare hereditary bone disorder of osteopetrosis, reduced bone resorption function leads to both the development of densely sclerotic fragile bones and progressive obliteration of the marrow spaces and cranial foramina. Marrow obliteration, typically associated with extramedullary hemopoiesis and hepatosplenomegaly, results in anemia and thrombocytopenia and nerve entrapment accounts for p...

Osteoblasts in the Vicinity of Osteoclasts in a Case of Infantile Osteopetrosis

Infantile metaphysial dysplasia or "battered babies"? A reassessment of material in the Fairbank Collection.

The Fairbank Collection in the Radiology Department of the Royal National Orthopaedic Hospital contains details of 15 patients in the section labelled "Metaphysial Dysplasia and Dysostosis". This material has been reviewed, long-term follow-up of the patients carried out and the diagnosis revised, where indicated, according to current concepts. Of the 15 patients, all children, seven had recogn...

Osteopetrosis Complicated by Maxillary Osteomyelitis: A Case Report

Introduction: Maxillary osteomyelitis is a rare phenomenon. If it occurs, evaluation for underlying disease especially osteopetrosis must be considered. Osteomyelitis occurs as a complication in 10% of the cases of osteopetrosis. Case report: This is a case report of maxillary osteomyelitis presented in a 15-year old boy with osteopetrosis.  In this case, the disease represented mainly with ...